Exploring typical and atypical variants of celiac disease: a narrative review

• Published in: International journal of research in medical sciences Vol. 12; no. 1; pp. 315 - 320
• Main Authors: Oza, Yugam R., Hassan, Hussein Abdikadir, Joshi, Helly Mayankkumar, Siddiqui, Aisha, Siddiqui, Farina Fartima, Gul, Muhammad Hamza
• Format: Journal Article
• Language: English
• Published: 28.12.2023
• ISSN: 2320-6071; 2320-6012
• DOI: 10.18203/2320-6012.ijrms20234028

There are many different clinical manifestations of celiac disease (CD), including the classical form, in which intestinal symptomatology predominates on the contrary there is atypical forms, in which extra-intestinal clinical features predominate, and the silent form, in which there are no clinical symptoms. Few or no gastrointestinal symptoms and a predominance of extra-intestinal features, including liver, kidney, skeletal, psychiatric, neurologic, dermatologic, hematologic, endocrinological, and reproductive involvements, define the atypical forms of the disease. Through screening high-risk groups, silent presentations of CD may be found. It is crucial for healthcare professionals to have a high level of suspicion for the atypical presentations of CD because it is now well known that CD may account for a number of chronic health issues.