Nocturnal enuresis — a new look at the old problem

Nocturnal enuresis is the most common functional disorder of the urinary system in children, significantly reducing the quality of life of both patients and their parents. There are several hypotheses for the development of this disease, none of which can be taken as dominant. In this regard, Noctur...

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Bibliographic Details
Published inUrology reports (St. - Petersburg) Vol. 12; no. 4; pp. 347 - 356
Main Authors Smirnova, Natalia N., Belyakova, Alla V., Kuprienko, Natalia B., Nikolskaya, Tatyana I.
Format Journal Article
LanguageEnglish
Published 22.01.2023
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Summary:Nocturnal enuresis is the most common functional disorder of the urinary system in children, significantly reducing the quality of life of both patients and their parents. There are several hypotheses for the development of this disease, none of which can be taken as dominant. In this regard, Nocturnal enuresis is considered as a polyetiological condition. This review details the main factors that are associated with the development of nocturnal enuresis in children. These include hereditary predisposition, bladder dysfunction, sleep and awakening disorders, delayed maturation of central nervous system structures, disruption of the circadian rhythm of antidiuretic hormone and aquaporin-2 production. Despite many publications on nocturnal enuresis in children, many aspects of the pathogenesis of the disease remain unclear and require further study.
ISSN:2225-9074
2687-1416
DOI:10.17816/uroved112569