Update on the aetiopathogenesis of obstructive sleep apnea: Role of inflammatory and immune mediated mechanisms

Obstructive sleep apnea (OSA) is often a lifestyle disease associated with obesity, which is rapidly evolving as a major health concern with diverse multisystemic implications. To prevent and mitigate its adverse effects and reduce its burden on society, its aetiopathogeneses must be precisely under...

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Published inWorld journal of clinical cases Vol. 12; no. 35; pp. 6754 - 6759
Main Authors Nag, Deb Sanjay, Varghese, Koshy, Swain, Amlan, Patel, Roushan, Sahu, Seelora, Sam, Merina
Format Journal Article
LanguageEnglish
Published 16.12.2024
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Summary:Obstructive sleep apnea (OSA) is often a lifestyle disease associated with obesity, which is rapidly evolving as a major health concern with diverse multisystemic implications. To prevent and mitigate its adverse effects and reduce its burden on society, its aetiopathogeneses must be precisely understood. Numerous studies focusing on the range of diverse anatomic, functional, and lifestyle factors have already been carried out to determine the possible contributory roles of these factors in OSA. Recently, evidence to validate the role of inflammatory pathways and immune mechanisms in the aetiopathogeneses of OSA is being developed. This allows for further research and translation of such knowledge for targeted therapeutic and preventive interventions in patients with or who are at risk of developing OSA.
ISSN:2307-8960
2307-8960
DOI:10.12998/wjcc.v12.i35.6754