A case of canine epitheliotropic lymphoma (mycosis fungoides)

The clinical picture, diagnosis and treatment of a dog with epitheliotropic lymphoma are presented. The dog (male, mongrel, 13-year old) was admitted to our Clinic with a 5-month history of non-pruritic skin lesions. At clinical examination a multifocal to diffuse exfoliative erythrodermia was the m...

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Published inJournal of the Hellenic Veterinary Medical Society Vol. 52; no. 4; p. 286
Main Authors SARIDOMICHELAKIS (Μ. Ν. ΣΑΡΙΔΟΜΙΧΕΛΑΚΗΣ), M. N., KOUTINAS (X.K. ΚΟΥΤΙΝΑΣ), C. K., KOUTINAS (Α. Φ. ΚΟΥΤΙΝΑΣ), A. F.
Format Journal Article
LanguageEnglish
Published 31.01.2018
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Summary:The clinical picture, diagnosis and treatment of a dog with epitheliotropic lymphoma are presented. The dog (male, mongrel, 13-year old) was admitted to our Clinic with a 5-month history of non-pruritic skin lesions. At clinical examination a multifocal to diffuse exfoliative erythrodermia was the most striking finding. Diagnosis of epitheliotropic lymphoma was based on cutaneous histopathology, revealing a dense dermal and epidermal lymphocytic infiltration and Pautrie microabcess formation. Initial treatment with isotretinoin had a poor impact on skin lesions that progressed to the macular stage. On the contrary, combination chemotherapy with Lasparaginase and isotretinoin resulted in substantial improvement. The animal died, following a short period of depression and inappetance, 15 months after the first appearance of skin lesions and 10 months after diagnosis.
ISSN:1792-2720
2585-3724
DOI:10.12681/jhvms.15459