Antimicrobial Agent‐ C ontaining Polymeric Materials

Summary Crosslinked poly(methyl methacrylate/ethylene glycol dimethacrylate) P(MMA/EGDMA) nanoparticles (NPs) loaded with the antimicrobial agent methyl paraben (MP) were prepared by miniemulsion polymerization. The MP‐loaded NPs (i.e., ≤9.63 wt% MP) had an average size in the range of 108 to 145 nm...

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Bibliographic Details
Published inMacromolecular symposia. Vol. 331-332; no. 1; pp. 144 - 151
Main Authors Karakosta, Paraskevi, Koumlili, Eleni, Kammona, Olga, Kiparissides, Costas
Format Journal Article
LanguageEnglish
Published 01.10.2013
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Summary:Summary Crosslinked poly(methyl methacrylate/ethylene glycol dimethacrylate) P(MMA/EGDMA) nanoparticles (NPs) loaded with the antimicrobial agent methyl paraben (MP) were prepared by miniemulsion polymerization. The MP‐loaded NPs (i.e., ≤9.63 wt% MP) had an average size in the range of 108 to 145 nm. The NPs were subsequently incorporated in a low‐density polyethylene (LDPE) matrix, in the form of individual NPs and small aggregates (<1 µm), employing a twin screw extrusion process in the presence and absence of appropriate compatibilizers (i.e., montmorillonite clay (MMT), mesoporous silica (MCM‐41)). MP exhibited a sustained release profile from the P(MMA/EGDMA) (NPs) as well as from the LDPE matrix.
ISSN:1022-1360
1521-3900
DOI:10.1002/masy.201300085