Signals of Death - Post-Diagnostic Single Gene Expression Trajectories in Breast Cancer - A Proof of Concept

Using the time-dependent dynamics of gene expression from immune cells in blood, we aimed to explore single gene expression trajectories as biomarkers for death after a diagnosis of breast cancer introducing a new statistical method denoted Difference in Time Development Statistics (DTDS). This show...

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Bibliographic Details
Main Authors Lund, Eiliv, Holden, Marit, Thalabard, Jean-Christophe, Rasmussen Busund, Lill-Tove, Snapkov, Igor, Holden, Lars
Format Book
LanguageEnglish
Published Universitetsforlaget 2020
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Summary:Using the time-dependent dynamics of gene expression from immune cells in blood, we aimed to explore single gene expression trajectories as biomarkers for death after a diagnosis of breast cancer introducing a new statistical method denoted Difference in Time Development Statistics (DTDS). This shows as proof of principle that the gene expression profiles from immune cells in blood differed in the postdiagnostic period are dependent on later vital status.
Bibliography:ERC-European Research Council: ERC-AdG 232997 TICE
ISBN:8215041191
9788215041193