Magnetic nanoparticles supported cinchona alkaloids for asymmetric Michael addition reaction of 1,B-dicarbonyls and maleimides

Magnetic nanoparticles Fe3O4@SiO2 supported cinchona alkaloids （quinine and quinidine） were successfully synthesized as magnetically recoverable organocatalysts and characterized by FT-IR, XPS, SEM measurements, and elemental analysis. Their catalytic activity and stereoselectivity were preliminaril...

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Bibliographic Details
Published in中国化学快报：英文版 Vol. 29; no. 1; pp. 201 - 204
Main Author Shi-Xuan Cao;Jia-Xi Wang;Zheng-Jie He
Format Journal Article
LanguageEnglish
Published 2018
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Summary:Magnetic nanoparticles Fe3O4@SiO2 supported cinchona alkaloids （quinine and quinidine） were successfully synthesized as magnetically recoverable organocatalysts and characterized by FT-IR, XPS, SEM measurements, and elemental analysis. Their catalytic activity and stereoselectivity were preliminarily evaluated in the asymmetric Michael addition reaction of 1,3-dicarbonyls and maleimides. The supported quinine catalyst exhibited good catalytic efficiency and modest to high enantioselectivity. The magnetic recoverabiliW and recyclability of the catalyst were also examined.
Bibliography:Magnetic nanoparticles Fe3O4@SiO2 supported cinchona alkaloids （quinine and quinidine） were successfully synthesized as magnetically recoverable organocatalysts and characterized by FT-IR, XPS, SEM measurements, and elemental analysis. Their catalytic activity and stereoselectivity were preliminarily evaluated in the asymmetric Michael addition reaction of 1,3-dicarbonyls and maleimides. The supported quinine catalyst exhibited good catalytic efficiency and modest to high enantioselectivity. The magnetic recoverabiliW and recyclability of the catalyst were also examined.
11-2710/O6
Magnetic nanoparticlesCinchona alkaloidsImmobilizationMichael additionAsymmetric catalysis
ISSN:1001-8417
1878-5964