皮肤Rosai-Dorfman病2例并文献复习

例1女,44岁,背部结节并斑块半年。例2女,25岁,面部结节1个月。皮损组织病理均显示:真皮内病变区域呈深染区和浅染区相间分布,可见组织细胞“伸入运动”。免疫组织化学示:组织细胞CD68及S100(+),CDla(-)。诊断:皮肤Rosai—Dorfman病。采取手术切除皮损治疗,随访2年,未见复发。...

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Bibliographic Details
Published in中国皮肤性病学杂志 Vol. 31; no. 10; pp. 1109 - 1111
Main Author 贾金靖 张海涛 郑焱
Format Journal Article
LanguageChinese
Published 2017
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Summary:例1女,44岁,背部结节并斑块半年。例2女,25岁,面部结节1个月。皮损组织病理均显示:真皮内病变区域呈深染区和浅染区相间分布,可见组织细胞“伸入运动”。免疫组织化学示:组织细胞CD68及S100(+),CDla(-)。诊断:皮肤Rosai—Dorfman病。采取手术切除皮损治疗,随访2年,未见复发。
Bibliography:A 44-year old female patient presented with nodules and plaques on the back for 6 months. A 25-year old fe- male patient presented with a nodule on the face for 1 month. Histopathology showed dark and light staining areas distributing at intervals in dermis. "Emperipolesis" of histocytes could be found. The immunohisto- chemical examination of S100 and CD68 were positive and CD1 a was negative in histocytes. The final diagno- sis was cutaneous Rosai-Dorfman disease. Operative resections were adopted and no recurrence could be found during the 2 years' follow-up.
JIA Jin-jing,ZHANG Hai-tao,ZHENG Yan ( Department of Dermatology, the Second Affiliated Hospital of Xi' an Jiaotong University, Xi' an 710004, China)
Sinus histiocytosis with massive lymphadenopathy; Rosai-Dorfman Disease; Histioeytosis ; Emperipolesis
61-1197/R
ISSN:1001-7089