主动脉内球囊反搏对急性ST段抬高型心肌梗死患者死亡率的影响

目的评价急性ST段抬高型心肌梗死（STEMI）患者在主动脉内球囊反搏（IABP）辅助下进行介入治疗的安全性及临床疗效。方法回顾性分析全军医院心血管介入诊疗管理系统中的资料。选取接受急诊PCI的8878例STEMI患者为研究对象,按是否接受IABP治疗分为IABP组（732例）和对照组（8146例）。对两组的基线资料进行对比分析。采用倾向配对分析对IABP组和对照组进行1：1倾向匹配,分析两组术中死亡、院内死亡、支架内血栓、出血等情况的差异。结果二元logistic回归分析显示,年龄、心力衰竭、肾功能不全是院内死亡的危险因素;通过1：1倾向匹配分析,发现两组术中死亡率、术后出血发生率、支架内血栓...

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Published in解放军医学杂志 Vol. 41; no. 6; pp. 441 - 445
Main Author 洪泰连 徐凯 荆全民 王守力 刘慧亮 李田昌 甘继宏 郑强荪 杨星昌 任江 曾春雨 宋治远 项军 拓步雄 罗助荣 梁春 姜东炬 宗刚军 武利军 柏书轶 田孝祥 韩雅玲
Format Journal Article
LanguageChinese
Published 2016
Subjects
医院死亡率
反搏动术
心肌梗死
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Summary:目的评价急性ST段抬高型心肌梗死（STEMI）患者在主动脉内球囊反搏（IABP）辅助下进行介入治疗的安全性及临床疗效。方法回顾性分析全军医院心血管介入诊疗管理系统中的资料。选取接受急诊PCI的8878例STEMI患者为研究对象,按是否接受IABP治疗分为IABP组（732例）和对照组（8146例）。对两组的基线资料进行对比分析。采用倾向配对分析对IABP组和对照组进行1：1倾向匹配,分析两组术中死亡、院内死亡、支架内血栓、出血等情况的差异。结果二元logistic回归分析显示,年龄、心力衰竭、肾功能不全是院内死亡的危险因素;通过1：1倾向匹配分析,发现两组术中死亡率、术后出血发生率、支架内血栓发生率差异均无统计学意义（P〉0.05）,而IABP组的院内死亡率明显高于对照组（10.4%vs2.5%,P〈0.05）。结论 IABP不能降低接受急诊介入治疗的STEMI患者的院内死亡率。
Bibliography:Objective To evaluate the clinical efficacy and safety of intra-aortic balloon pump（IABP） counterpulsation for the patients with acute ST-elevated myocardial infarction（STEMI）. Methods To retrospectively analyze the data collected from the Management System of Cardiovascular Interventional Treatment in Military Hospitals. A total of 8878 consecutive patients with acute STEMI undergoing percutaneous coronary intervention（PCI） were recruited in present study, of whom 732 patients received IABP therapy were assigned into IABP group and the other 8146 patients received no IABP into control group. Contrastive analysis was performed to analyze the baseline data of the two groups, and 1：1 propensity matching was done to compare the differences between the two groups of intraoperative mortality, in-hospital mortality, stent thrombosis and postoperative hemorrhage. Results Multi-logistic regression revealed that age, heart failure and renal dysfunction were the risk factors for in-hospital mortality. By 1：1 propensity
ISSN:0577-7402