TheArabidopsis RING Domain Protein BOI Inhibits Flowering via CO-dependent and CO-independent Mechanisms

BOTRYTIS SUSCEPTIBLE1 INTERACTOR （BOI） and its three homologs （BOIs） are RING domain-containing proteins that repress flowering. Here, we investigated how BOIs repress flowering. Genetic analysis of the boiQ quadruple mutant indicates that BOIs repress flowering mainly through FLOWERING LOCUS T （FT）...

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Published in分子植物：英文版 Vol. 8; no. 12; pp. 1725 - 1736
Main Author Khoa Thi Nguyen Jeongmoo Park Eunae Park Ilha Lee Giltsu Choi
Format Journal Article
LanguageEnglish
Published 2015
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Summary:BOTRYTIS SUSCEPTIBLE1 INTERACTOR （BOI） and its three homologs （BOIs） are RING domain-containing proteins that repress flowering. Here, we investigated how BOIs repress flowering. Genetic analysis of the boiQ quadruple mutant indicates that BOIs repress flowering mainly through FLOWERING LOCUS T （FT）. BOIs repress the expression of FT by CONSTANS （CO）-dependent and -independent mechanisms： in the CO-dependent mechanism, BOIs bind to CO, inhibit the targeting of CO to the FT locus, and thus repress the expression of FT; in the CO-independent mechanism, BOIs target the FT locus via a mechanism that requires DELLAs but not CO. This dual repression of FT makes BOIs strong repressors of flowering in both CO-dependent and CO-independent pathways in Arabidopsis thaliana. Our finding that BOIs inhibit CO targeting further suggests that, in addition to modulating CO mRNA expression and CO protein stability, flowering regulation can also modulate the targeting of CO to FT.
Bibliography:31-2013/Q
CO, BOI, DELLA, flowering, DNA binding
BOTRYTIS SUSCEPTIBLE1 INTERACTOR （BOI） and its three homologs （BOIs） are RING domain-containing proteins that repress flowering. Here, we investigated how BOIs repress flowering. Genetic analysis of the boiQ quadruple mutant indicates that BOIs repress flowering mainly through FLOWERING LOCUS T （FT）. BOIs repress the expression of FT by CONSTANS （CO）-dependent and -independent mechanisms： in the CO-dependent mechanism, BOIs bind to CO, inhibit the targeting of CO to the FT locus, and thus repress the expression of FT; in the CO-independent mechanism, BOIs target the FT locus via a mechanism that requires DELLAs but not CO. This dual repression of FT makes BOIs strong repressors of flowering in both CO-dependent and CO-independent pathways in Arabidopsis thaliana. Our finding that BOIs inhibit CO targeting further suggests that, in addition to modulating CO mRNA expression and CO protein stability, flowering regulation can also modulate the targeting of CO to FT.
ISSN:1674-2052
1752-9867