Synthesis of Terphenyl Derivatives by Pd-Catalyzed Suzuki-Miyaura Reaction of Dibromobenzene Using 2N20-Salen as a Ligand in Aqueous Solution
A simple and efficient catalytic system for Na2PdC14 catalyzing the Suzuki-Miyaura reaction of dibromoben- zene and arylboronic acid has been developed by using 2N2O-salen as a ligand in H2O/EtOH (V : V=4 : 1) at 100 ℃. Using this method, the reactions of substrates containing sterically demanding o...
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Published in | 中国化学:英文版 no. 10; pp. 1189 - 1193 |
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Main Author | |
Format | Journal Article |
Language | English |
Published |
2015
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Subjects | |
Online Access | Get full text |
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Summary: | A simple and efficient catalytic system for Na2PdC14 catalyzing the Suzuki-Miyaura reaction of dibromoben- zene and arylboronic acid has been developed by using 2N2O-salen as a ligand in H2O/EtOH (V : V=4 : 1) at 100 ℃. Using this method, the reactions of substrates containing sterically demanding ortho substituents (e.g. dibromo- benzene and/or arylboronic acids) proceeded efficiently, with the corresponding terphenyl derivatives being pro- duced in moderate to excellent yields. Furthermore, this method offers interesting features for the multi-gram scale synthesis of terphenyl compound. |
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Bibliography: | terphenyls, synthesis, 2N2O-salen, palladium, catalyze, Suzuki-Miyaura reaction A simple and efficient catalytic system for Na2PdC14 catalyzing the Suzuki-Miyaura reaction of dibromoben- zene and arylboronic acid has been developed by using 2N2O-salen as a ligand in H2O/EtOH (V : V=4 : 1) at 100 ℃. Using this method, the reactions of substrates containing sterically demanding ortho substituents (e.g. dibromo- benzene and/or arylboronic acids) proceeded efficiently, with the corresponding terphenyl derivatives being pro- duced in moderate to excellent yields. Furthermore, this method offers interesting features for the multi-gram scale synthesis of terphenyl compound. 31-1547/O6 |
ISSN: | 1001-604X 1614-7065 |