TMSCI Promoted Direct sp3 C-H Alkenylation to Construct （E）-2-Styryl-tetrahydrobenzo[d]thiazoles

• Published in: 中国化学：英文版 no. 9; pp. 1077 - 1083
• Main Author: Chengqiao CaO Wenbin Wang Fan Zhang Nianyu Huang Kun Zou
• Format: Journal Article
• Language: English
• Published: 2015
• Subjects: sp3; X射线衍射分析; 三甲基氯硅烷; 噻唑; 官能团转化; 烯基化反应; 生物制备; 苯乙烯

A high-efficient and stereo-specific approach for the preparation of biologically important （E）-2-styryl-tetra- hydrobenzo[d]thiazoles has been developed via TMSC1 promoted direct sp3 C-H alkenylation of 2-methyl-5,6-di- hydrobenzo[d]thiazol-7（4H）-one under metal-free conditions. Seventeen target co...