Outcomes of T3a Prostate Cancer with UnfavorablePrognostic Factors Treated with BrachytherapyCombined with External Radiotherapyand Hormone Therapy

Objective To evaluate the outcomes of T3a prostate cancer with unfavorable prognostic factorstreated with permanent interstitial brachytherapy combined with external radiotherapy and hormonetherapy.Methods From January 2003 to December 2008, 38 patients classified as T3a prostate cancer withunfavora...

Full description

Saved in:
Bibliographic Details
Published in中国医学科学杂志：英文版 no. 3; pp. 143 - 149
Main Author Zhi-peng Mai Wei-gang Yan Han-zhong Li Yi Zhou Zhi-en Zhou
Format Journal Article
LanguageEnglish
Published 2015
Subjects
neoplasms
prostatic
T3a
thera
trimodality
unfavorable
Online AccessGet full text

Cover

More Information
Summary:Objective To evaluate the outcomes of T3a prostate cancer with unfavorable prognostic factorstreated with permanent interstitial brachytherapy combined with external radiotherapy and hormonetherapy.Methods From January 2003 to December 2008, 38 patients classified as T3a prostate cancer withunfavorable prognostic factors were treated with trimodality therapy （brachytherapy ＋ external radiotherapy＋ hormone therapy）. The prescription dose of brachytherapy and external radiotherapy were 110 Gy and 45Gy, respectively. The duration of hormone therapy was 2-3 years. The endpoints of this study includedbiochemical failure-free survival （BFFS）, distant metastasis-free survival （DMFS）, cancer-specific survival（CSS）, and overall survival （OS）. Survival curves were calculated using the Kaplan-Meier method. TheLog-rank test was used to identify the prognostic predictors for univariate analysis.
Bibliography:11-2752/R
ISSN:1001-9294