Fission yeast telomere-binding protein Tazl is a functiona out not a structural counterpart of human TRF1 and TRF2

• Published in: 细胞研究：英文版 no. 7; pp. 881 - 884
• Main Author: Wei Deng Jian Wu Feng Wang Junko Kanoh Pierre-Marie Dehe Haruna Inoue Juan Chen Ming Lei
• Format: Journal Article
• Language: English
• Published: 2015
• Subjects: C-末端; DNA结合结构域; 人类; 哺乳动物细胞; 端粒结合蛋白; 细胞活力; 结构相; 裂殖酵母

Dear Editor, Telomeres, the natural ends of linear eukaryotic chro- mosomes, are essential for cell viability and genome integrity [ 1 ]. In mammalian cells, telomere repeat factors 1 and 2 （TRF1 and TRF2） are the first two identified mammalian telomere-binding proteins that play essential roles in...