Role of Matrix Metalloproteinase- 1 （MMP- 1）/Protease-activated Receptor-1 （PAR-1）Signaling Pathway in the Cervical Cancer Invasion

• Published in: 生殖与避孕：英文版 no. 1; pp. 18 - 25
• Main Author: Ning-xia SUN Qian ZHAO Chen YE Yan MA Wen LI
• Format: Journal Article
• Language: English
• Published: 2014
• Subjects: Hela细胞; MMP-1; RT-PCR方法; 信令; 入侵途径; 基质金属蛋白酶; 宫颈癌; 蛋白酶激活受体

Objective To investigate the role of matrix metalloproteinase-1 （MMP-1）/protease- activated receptor-1 （PAR-l） signaling in the cervical cancer invasion. Methods RT-PCR was used to test the mRNA level of MMP-1 in 59 cases of cervical squamous cell cancer. Cell invasion was evaluated by Transwell ass...