Mechanism underlying the protective effect of Kaixin lieyu Fang on vascular depression following cerebral white matter damage

• Published in: 中国神经再生研究：英文版 Vol. 9; no. 1; pp. 61 - 68
• Main Author: Ying Zhang Shijing Huang Yanyun Wang Junhua Pan Jun Zheng Xianhui Zhang Yuxia Chen Duojiao Li
• Format: Journal Article
• Language: English
• Published: 2014
• Subjects: Bax蛋白; Bcl-2蛋白; mRNA表达; 保护作用; 抑郁症; 损伤机制; 脑白质; 血管

The Chinese compound Kaixin fieyu Fang can be used to treat vascular depression; however, the underlying mechanism remains unclear. This study established a rat model of chronic cerebral ischemia-caused white matter damage by ligation of the bilateral common carotid arteries. Rats received daily int...