甘肃棘豆对小鼠的急性毒性研究

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Published in植物病虫害研究：英文版 no. 5; pp. 59 - 60
Main Author 赵剑喜 刘晔玮 李丽 黄新异 柳军玺 邸多隆
Format Journal Article
LanguageEnglish
Published 2011
Subjects
急性毒性
最大耐受量
甘肃棘豆
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ISSN2152-3932

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Bibliography:ZHAO Jian-xi, LIU Ye-wei, LI Li, HUANG Xin-yi, LIU Jun-xi, DI Duo-long（1. Institute of Nutrition and Food Hygiene, School of Public Health, Lanzhou University, Lanzhou 730000, China; 2. Key Laboratory of Chemistry of North- western Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Chinese Academy of Sciences, Lanzhou 730000, China）
[ Objective] The paper was to study the acute toxicity of Oxytropis Kansuensis Bunge on rats. [ Method ] Forty rats were randomly divided into two gToups： control group （distilled water） and trial group （water extract of 0. Kansuens/s） to carry out the acute toxicity experiment. The trial group was supplied with the maximum dose （6.0 g/ml,0.8 ml/20 g） twice per day for continuous 7 d. [Result] The maximal tolerance dose of rats to water extract of O. Kansuens/s was more than 480 g/kg. Feeding rats with O. Kansuens/s would not lead to the death of rats within short time （7 d） and no obvious macroscopic pathological changes in the viscera of rats could be seen in naked eyes. [Condusion] The study provided theoretical basis for full use of O. Kansuens/s resources.
Oxytropis Kansuensis Bunge;Acute toxicity;Maximum tolerated dose; China
ISSN:2152-3932