Synthesis and Herbicidal Activity of Novel N-（2-Fluoro-5（3- methyl-2,6-dioxo-4-（trifluoromethyl）-2,3-dihydro-pyrimidin- l（6H）-yl）phenyl）-2-phenoxyacetamide Derivatives

Thirteen novel N-（2-fluoro-5-（3-methyl-2,6-dioxo-4-（trifluoromethy）-2,3-dihydropyrimidin-1（6H）-yl）phenyl）- 2-phenoxy）acetamides were designed and synthesized utilizing 4-fluoro-aniline and ethyl 3-amino-4,4,4-trifluoro-but-2-enoate as starting materials. The chemical structures of all compounds were...

Full description

Saved in:
Bibliographic Details
Published in中国化学：英文版 Vol. 29; no. 11; pp. 2401 - 2406
Main Author 吴道新 孙炯 黄明智 莫洪波 王晓光 李宏伟 任叶果 胡志彬 何莲 尹笃林
Format Journal Article
LanguageEnglish
Published 2011
Subjects
三氟甲基
二氢
双子叶杂草
合成
苯基
苯氧基
衍生物
除草活性
Online AccessGet full text

Cover

More Information
Summary:Thirteen novel N-（2-fluoro-5-（3-methyl-2,6-dioxo-4-（trifluoromethy）-2,3-dihydropyrimidin-1（6H）-yl）phenyl）- 2-phenoxy）acetamides were designed and synthesized utilizing 4-fluoro-aniline and ethyl 3-amino-4,4,4-trifluoro-but-2-enoate as starting materials. The chemical structures of all compounds were confirmed by IH NMR, IR, mass spectrum and elemental analyses. Subsequently, the herbicidal activities of the as-prepared compounds were evalu-ated in the greenhouse. Bioassay results indicated that most of compounds had better herbicidal activities against dicotyledonous weeds. Among all the tested compounds, compounds 4a--4i showed good herbicidal activities at both pre-emergence and post-emergence treatment against two or three kinds of dicotyledonous weeds, such as Abutilon theophrasti Medic, Amaranthus ascendens L, and Chenopodium album L at the dosage of 75 g ai/ha.
Bibliography:31-1547/O6
Wu, Daoxin Sun, Jiong Huang, Mingzhi Mo, Hongbo Wang, Xiaoguang Li, Hongwei Ren, Yeguo Hu, Zhibing He, Lian Yin, Dulin a School of Chemistry and Biological Engineering, Changsha University of Science and Technology, Changsha Hunan 410114, China b National Engineering Research Center for Agrochemicals, Hunan Research Institute of Chemical Industry, Changsha, Hunan 410007, China c Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research （Ministry of Education of China）, Hunan Normal University, Changsha, Hunan 410081, China
synthesis design, 2,6-dioxo-4-（trifluoromethyl）-2,3-dihydropyrimidine, N-phenyl-2-phenoxyacetamide, synthesis, herbicidal activity
Thirteen novel N-（2-fluoro-5-（3-methyl-2,6-dioxo-4-（trifluoromethy）-2,3-dihydropyrimidin-1（6H）-yl）phenyl）- 2-phenoxy）acetamides were designed and synthesized utilizing 4-fluoro-aniline and ethyl 3-amino-4,4,4-trifluoro-but-2-enoate as starting materials. The chemical structures of all compounds were confirmed by IH NMR, IR, mass spectrum and elemental analyses. Subsequently, the herbicidal activities of the as-prepared compounds were evalu-ated in the greenhouse. Bioassay results indicated that most of compounds had better herbicidal activities against dicotyledonous weeds. Among all the tested compounds, compounds 4a--4i showed good herbicidal activities at both pre-emergence and post-emergence treatment against two or three kinds of dicotyledonous weeds, such as Abutilon theophrasti Medic, Amaranthus ascendens L, and Chenopodium album L at the dosage of 75 g ai/ha.
ISSN:1001-604X
1614-7065