A Randomized Double-blind Placebo-controlled Study of Pu＇er Tea（普洱茶） Extract on the Regulation of Metabolic Syndrome

• Published in: 中国结合医学杂志：英文版 Vol. 17; no. 7; pp. 492 - 498
• Main Author: 褚松龄 富宏 杨金霞 刘庚信 窦攀 张良 屠鹏飞 王学美
• Format: Journal Article
• Language: English
• Published: 2011
• Subjects: 代谢综合征; 低密度脂蛋白; 普洱茶; 茶提取物; 血清总胆固醇; 规例; 超氧化物歧化酶; 随机
• ISSN: 1672-0415; 1993-0402

Objective：To explore the regulative efficacy of Pu＇er tea（普洱茶）extract on metabolic syndrome. Methods：Ninety patients with metabolic syndrome were randomly divided into two groups,the intervention group administered with Pu＇er tea extract,and the placebo group with placebo capsules.After 3 months＇ treatment, body mass index,waist hip ratio,blood lipids,blood sugar,immune and inflammatory index,and oxidation index of the patients with metabolic syndrome were tested and analyzed.Results：In the intervention group,the body mass index,waist-hip ratio,fasting and 2 h postprandial blood glucose,serum total cholesterol,triglycerides, low density lipoprotein and apolipoprotein B-100 all decreased in the patients with metabolic syndrome,and also the high-density lipoprotein level increased and apolipoprotein A-1 showed the tendency to increase. Serum C-reactive protein,tumor necrosis factor-α,and interleukin-6 were decreased in the intervention group. lnterleukin-10 level was increased,MDA was decreased and superoxide dismutase was increased.Compared with before treatment and the placebo group,there were significant differences（P0.05,P0.01）.Conclusions： Pu＇er tea demonstrated excellent potential in improving central obesity,adjusting blood lipid,lowering blood sugar,regulating immunity and resisting oxidation.It can adjust the metabolic syndrome of different clinical phenotypes to different degrees,and is ideally fit for early prevention of metabolic syndrome.