Prognosis of 980 patients with gastric cancer after surgical resection

• Published in: Ai zheng no. 11; pp. 923 - 930
• Main Author: Wei Wang Yuan-Fang Li Xiao-Wei Sun Ying-Bo Chen Wei Li Da-Zhi Xu Xuan-Xiang Guan Chun-Yu Huang You-Qing Zhan Zhi-Wei Zhou
• Format: Journal Article
• Language: Chinese
• Published: 2010
• Subjects: TNM; 单因素分析; 多因素分析; 恶性肿瘤; 手术切除; 淋巴结; 胃癌; 预后
• ISSN: 1000-467X; 1944-446X

Background and Objective： Although surgery is the only possible means to cure gastric cancer, the prognosis is often discrepant. The American Joint Committee on Cancer/International Union against Cancer （AJCC/UICC） published the TNM classification of Malignant Tumors （seventh edition） for gastric cancer recently. This study aimed to use this new edition staging system to investigate the prognostic factors for gastric cancer. Methods： The clinicopathologic data of 980 patients with gastric cancer treated by surgical resection in our hospital between January 2000 and December 2006 were analyzed retrospectively. The overall survival rate was determined by using Kaplan-Meier method and log-rank test was used to determine significance. The prognosis was analyzed using univariate analysis and multivariate analysis with the Cox proportional hazards model. The 6th and 7th edition AJCC/UICC TNM staging systems were used to compare the survival outcomes for the cohort of patients. Results： The overall 1-, 3-, 5-year su