Hypereosinophilia with a giant thrombus in the right ventricle: Loffler endocarditis in an ll-year-old girl

Hypereosinophilic syndrome (HES) is a rare disorder that can be seen in various organ systems, but its major tissue target is the heart.' The most characteristic cardiovascular abnormality in HES is endomyocardial fibrosis, initially described in 1936 by Loffler, who called it "fibroplastic parietal...

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Bibliographic Details
Published inChinese medical journal Vol. 122; no. 23; pp. 2914 - 2916
Main Author GUO Yong-fang HAN Zhi-hong JIANG Teng-yong FANG Wei DONG Ran WU Xue-si
Format Journal Article
LanguageEnglish
Published 2009
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Summary:Hypereosinophilic syndrome (HES) is a rare disorder that can be seen in various organ systems, but its major tissue target is the heart.' The most characteristic cardiovascular abnormality in HES is endomyocardial fibrosis, initially described in 1936 by Loffler, who called it "fibroplastic parietal endocarditis with blood eosinophilia." The overall prognosis of patients with Loffler endocarditis is very poor. Current treatments include anticoagulation and anti-eosinophils therapy, and surgery only has been used in selected cases.
Bibliography:hypereosinophilic syndrome
Q463
11-2154/R
adolescent
hypereosinophilic syndrome; Loffler endocarditis; adolescent
Q592.1
Loffler endocarditis
ISSN:0366-6999
2542-5641