The Effects of IntracelluIar Glutathione Content on the Sensitivity of Methylseleninic Acid to Human High-metastatic Large Cell Lung Cancer Cell Line L9981
Background and Objective Lung cancer has the fastest increasing rate of morbidity and mortality all over the world and appears to be one of the most dangerous malignant tumors that is threatening human being's health and lives, it also has the lowest cure rate on all tumors. Although operation is th...
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Published in | Zhongguo fei ai za zhi Vol. 12; no. 6; pp. 510 - 511 |
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Main Author | |
Format | Journal Article |
Language | Chinese |
Published |
2009
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Subjects | |
Online Access | Get full text |
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Summary: | Background and Objective Lung cancer has the fastest increasing rate of morbidity and mortality all over the world and appears to be one of the most dangerous malignant tumors that is threatening human being's health and lives, it also has the lowest cure rate on all tumors. Although operation is the first choice to the early stage lung cancer, but searching for new antilung cancer drugs, especially the one with maximal effiiency and minimal toxicities is necessary to cure the advanced lung cancer and prolong the patients' lives. Selenium has been well known as an antioxidant in the nutritional range of intake, in many human clinical trials. Supra-nutritional selenium supplement has been shown to reduce risk of cancers of several organs, including lung cancer, there still has several clinical ongoing trials to confirm the cancer chemopreventive effects of selenium. |
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Bibliography: | Cellcycle R734.2 ROS Human high-metastatic large cell lung cancer lineL9981 Methylseleninic acid 12-1395/R Methylseleninic acid; Glutathione; Apoptosis; Cellcycle; ROS; Human high-metastatic large cell lung cancer lineL9981 Glutathione Apoptosis |
ISSN: | 1009-3419 1999-6187 |