The Difference of Gene Expression Profile in Human Large Cell Lung Cancer Cell Lines with Different Metastatic Potential
Background and Objective Lung cancer is the most lethal malignangy that threatens human heath and lives nowadays in the world, and meanwhile is also the one with worst clinical outcome. Invasion and metastasis of lung cancer is the leading cause of treatment failure and patients' deaths. Therefore t...
Saved in:
Published in | Zhongguo fei ai za zhi Vol. 12; no. 6; pp. 496 - 497 |
---|---|
Main Author | |
Format | Journal Article |
Language | Chinese |
Published |
2009
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Summary: | Background and Objective Lung cancer is the most lethal malignangy that threatens human heath and lives nowadays in the world, and meanwhile is also the one with worst clinical outcome. Invasion and metastasis of lung cancer is the leading cause of treatment failure and patients' deaths. Therefore the study of the molecular mechanisms of tumor invasion and metastasis has an important theoretical meaning and clinical application prospect. Invasion and metastasis of lung cancer is a complicated procedure with. interactions among tumor cells, human body and target tissues ,which is controlled by multiple genes and takes multiple steps to develop. A series of tumor associated genes and signal transduction pathways are also involved in this procedure. As for this large number of genes, traditional approaches such as Southern blot, North blot and RT-PCR have their limitations that can only study one or few genes and the simple interactions among them, |
---|---|
Bibliography: | Human large cell lung cancer R734.2 Metastasis Bioinformatics Human large cell lung cancer; Gene expression profile; Metastasis; Bioinformatics 12-1395/R Gene expression profile |
ISSN: | 1009-3419 1999-6187 |