Clinical Significance of a Rise in AFP in Lung Adenocarcinoma Patients with Liver Metastasis: One Case Report and Literatures Review

Introduction Usually the alpha fetoprotein (AFP) concentration of patients with metastatic liver cancer is slightly raised. Most of the levels are lower than 400 ug/L. Following biopsies of lung and liver neoplasms, one patient with a clinical diagnosis of lung cancer plus liver metastasis was patho...

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Bibliographic Details
Published inClinical oncology and cancer research Vol. 5; no. 3; pp. 226 - 228
Main Author Yue'an Cao Nanzhan Long Chaosheng Peng Ping Lu Jing Xia Wei Wang Wenxiu Xie
Format Journal Article
LanguageEnglish
Published 2008
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Summary:Introduction Usually the alpha fetoprotein (AFP) concentration of patients with metastatic liver cancer is slightly raised. Most of the levels are lower than 400 ug/L. Following biopsies of lung and liver neoplasms, one patient with a clinical diagnosis of lung cancer plus liver metastasis was pathologically diagnosed having an adenocarcinoma. His serum AFP value was 100-300 times the normal value. In order to further explore the clinical significance of an elevation of the AFP level in patients with lung adenocarcinoma plus liver metastasis, and to precisely distinguish a simple liver metastasis from lung adenocarcinoma or from lung hepatoid adenocarcinoma (HAC), a clinical analysis of the patient, and a literature review was conducted.
Bibliography:R734.2
12-1404/R
alpha fetoprotein, adenocarcinoma of the lung,metastatic liver cancer, hepatoid adenocarcinoma.
ISSN:1674-5361
1868-324X