Retinal pigment epithelial cells： biological property and application in Parkinson＇s disease

Parkinson＇s disease is a neurodegenerative disorder mainly caused by degeneration of the dopaminergic neurons in the substantia nigral pars compacta （SNpc）. The typical motor symptoms of this disease are tremor, akinesia, and rigidity, which are mostly caused by dysfunction of the nigro-striatal pat...

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Bibliographic Details
Published inChinese medical journal Vol. 120; no. 5; pp. 416 - 420
Main Author MING Ming LE Wei-dong
Format Journal Article
LanguageEnglish
Published 2007
Subjects
帕金森氏症
生物学
病理机制
视网膜色素细胞
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Summary:Parkinson＇s disease is a neurodegenerative disorder mainly caused by degeneration of the dopaminergic neurons in the substantia nigral pars compacta （SNpc）. The typical motor symptoms of this disease are tremor, akinesia, and rigidity, which are mostly caused by dysfunction of the nigro-striatal pathway. Dopaminergic neurons in the SNpc project long axons to caudate nucleus and the putamen, and secrete dopamine.
Bibliography:trophic factors
11-2154/R
R742.5
transplantation
retinal pigment epithelial cells
microcarrier
Parkinson＇s disease; transplantation; retinal pigment epithelial cells; microcarrier; trophic factors
Parkinson＇s disease
ISSN:0366-6999
2542-5641