The synthesis and pharmacology of some novel excitatory amino acid analogues

• Main Author: Badman, G. T
• Format: Dissertation
• Language: English
• Published: City of London Polytechnic 1986
• Subjects: 540 Chemistry & allied sciences; 610 Medicine & health

Certain amino acids, notably L-glutamate and L-aspartate, are believed to fulfil a role as excitatory neurotransmitters in the mammalian Central Nervous System (CNS). Investigation has revealed the presence of three, and possibly a fourth, type of receptor for such neurotransmitters. These receptors...