Parathyroid Glands and Hyperparathyroidism : A General Overview

Hyperparathyroidism (HPT) is a clinical condition caused by the increase of parathyroid hormone (PTH) synthesis by the parathyroid glands. PTH has a central and fundamental role in the control of calcium and phosphorus homeostasis. Its action on the kidney, bone, and, indirectly, intestinal cells im...

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Bibliographic Details
Main Author Casarim, Andre Luis Maion Luis Maion
Format Book Chapter
LanguageEnglish
Published 01.01.2020
Subjects
Biochemistry
Life Sciences
Science
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Summary:Hyperparathyroidism (HPT) is a clinical condition caused by the increase of parathyroid hormone (PTH) synthesis by the parathyroid glands. PTH has a central and fundamental role in the control of calcium and phosphorus homeostasis. Its action on the kidney, bone, and, indirectly, intestinal cells implies a rapid increase in extracellular calcium flow. This clinical condition may be due to an intrinsic parathyroid disorder or secondary to an imbalance of calcium metabolism in patients with systemic diseases, such as chronic renal failure. The treatment of hyperparathyroidism may be clinical, with the control of calcium, phosphorus, and PTH levels, or surgical, depending on the various forms presented. The purpose of the chapter is to discuss the types of hyperparathyroidism, their relationship with phosphorus and mainly calcium metabolism, as well as the main forms of diagnosis and treatment.
Bibliography:MODID-6d55e02e354:IntechOpen