Post-selection Inference in Regression Models for Group Testing Data

• Main Authors: Shen, Qinyan, Gregory, Karl, Huang, Xianzheng
• Format: Journal Article
• Language: English
• Published: 16.04.2025
• Subjects: Statistics - Methodology
• DOI: 10.48550/arxiv.2504.11767

Biometrics. 2024 Jul 1;80(3):ujae101 We develop methodology for valid inference after variable selection in logistic regression when the responses are partially observed, that is, when one observes a set of error-prone testing outcomes instead of the true values of the responses. Aiming at selecting important covariates while accounting for missing information in the response data, we apply the expectation-maximization algorithm to compute maximum likelihood estimators subject to LASSO penalization. Subsequent to variable selection, we make inferences on the selected covariate effects by extending post-selection inference methodology based on the polyhedral lemma. Empirical evidence from our extensive simulation study suggests that our post-selection inference results are more reliable than those from naive inference methods that use the same data to perform variable selection and inference without adjusting for variable selection.