Isolation and structure elucidation of novel natural products from Turkish lichens

• Published in: Turkish journal of chemistry Vol. 27; no. 4; pp. 493 - 500
• Main Authors: KIRMIZIGÜL, Süheyla, İÇLİ, Sıddık, ZEYBEK, Ulvi, ANIL, Hüseyin, KOZ, Ömer
• Format: Journal Article
• Language: English
• Published: TÜBİTAK 2003
• Subjects: Analitik Kimya, Ayırma Yöntemleri; Analytical Chemistry, Separation Methods; antibacterial action; Antibakteriyel etki; antifungal action; Antifungal etki; chemical analysis; chemical composition; chromatography; Evernia prunastri; Fenolik bileşikler; isolation[separation]; İzolasyon[ayırma]; Kimyasal analiz; Kimyasal bileşim; Kromatografi; Letharia vulpina; Lichen(plant); Liken(bitki); Organic Chemistry; Organik Kimya; phenolic compound; Pseudevernia furfuracea; spectroscopy; Spektroskopi
• ISSN: 1300-0527; 1303-6130

Three natural products were isolated from three different Turkish lichens. Microbiological investigations were also examined of these lichens. Compound 1 is known as 2-hydroxy-4-methoxy-3,6-dimethyl benzoic acid, and is isolated from Pseudevernia furfuracea for the first time. Compounds 2 and 3 are detected as new compounds and called, 3-acetyl-4-amino-2-chloro-1- (4-hydroxy-2-methoxy- 6-methylphenyl carbonyloxy) benzene and 2-(4-methoxyphenyl)-2-(5-oxo-4-phenyl-2,5- dihydro-2-furaniliden) acetic acid; they were isolated from Evernia prunastri and Letharia vulpina, respectively. All these compounds had different skeletons. Their structures were established by chemical methods and spectroscopic techniques using IR, UV, 1D and 2D NMR and EI and (+) FAB-Mass methods.