2.5D Thermometry Maps for MRI-Guided Tumor Ablation
Fast and reliable monitoring of volumetric heat distribution during MRI-guided tumor ablation is an urgent clinical need. In this work, we introduce a method for generating 2.5D thermometry maps from uniformly distributed 2D MRI phase images rotated around the applicator’s main axis. The images canb...
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Published in | Medical Image Computing and Computer Assisted Intervention – MICCAI 2021 pp. 311 - 320 |
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Main Authors | , , , , , , , |
Format | Book Chapter |
Language | English |
Published |
Cham
Springer International Publishing
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Series | Lecture Notes in Computer Science |
Subjects | |
Online Access | Get full text |
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Summary: | Fast and reliable monitoring of volumetric heat distribution during MRI-guided tumor ablation is an urgent clinical need. In this work, we introduce a method for generating 2.5D thermometry maps from uniformly distributed 2D MRI phase images rotated around the applicator’s main axis. The images canbe fetched directly from the MR device, reducing the delay between image acquisition and visualization. For reconstruction, we use a weighted interpolation on a cylindric coordinate representation to calculate the heat value of voxels in a region of interest. A pilot study on 13 ex vivo bio protein phantoms with flexible tubes to simulate a heat sink effect was conducted to evaluate our method. After thermal ablation, we compared the measured coagulation zone extracted from the post-treatment MR data set with the output of the 2.5D thermometry map. The results show a mean Dice score of 0.75±0.07\documentclass[12pt]{minimal}
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\begin{document}$$0.77\pm 0.03$$\end{document}, and a reconstruction time within 18.02 ms ± 5.91 ms. Future steps should address improving temporal resolution and accuracy, e.g., incorporating advanced bioheat transfer simulations. |
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Bibliography: | The work of this paper is funded by the Federal Ministry of Education and Research within the Forschungscampus STIMULATE under grant numbers ‘13GW0473A’ and ‘13GW0473B’. This work was also supported by PRACTIS - Clinician Scientist Program, funded by the German Research Foundation (DFG, ME 3696/3- 1).J. Alpers and D. Reimert—Joint first authorshipB. Hensen and C. Hansen—Joint senior authorship. |
ISBN: | 9783030872014 3030872017 |
ISSN: | 0302-9743 1611-3349 |
DOI: | 10.1007/978-3-030-87202-1_30 |