Stable Fast Rewiring Depends on the Activation of Skeleton Voxels

• Published in: Neural Information Processing pp. 1 - 8
• Main Authors: Song, Sanming, Yao, Hongxun
• Format: Book Chapter
• Language: English
• Published: Berlin, Heidelberg Springer Berlin Heidelberg
• Series: Lecture Notes in Computer Science
• Subjects: fMRI; functional network; rewiring
• ISBN: 364224954X; 9783642249549
• ISSN: 0302-9743; 1611-3349
• DOI: 10.1007/978-3-642-24955-6_1

Compared with the relatively stable structural networks, the functional networks, defined by the temporal correlation between remote neurophysiological events, are highly complex and variable. However, the transitions should never be random. So it was proposed that some stable fast rewiring mechanisms probably exist in the brain. In order to probe the underlying mechanisms, we analyze the fMRI signal in temporal dimension and obtain several heuristic conclusions. 1) There is a stable time delay, 7~14 seconds, between the stimulus onset and the activation of corresponding functional regions. 2) In analyzing the biophysical factors that support stable fast rewiring, it is, to our best knowledge, the first to observe that skeleton voxels may be essential for the fast rewiring process. 3) Our analysis on the structure of functional network supports the scale-free hypothesis.