Discovery and Annotation of Genetic Modules

Biological complexity, and the complexity of a cell in particular, scales only weakly with the number of components. Instead, a cell’s ability to process information, to respond and adapt to an environment in fugue, is directly related to the combinatorially large number of ways genes can be selecte...

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Bibliographic Details
Published inResearch in Computational Molecular Biology p. 188
Main Author DeLisi, Charles
Format Book Chapter
LanguageEnglish
Published Berlin, Heidelberg Springer Berlin Heidelberg 2005
SeriesLecture Notes in Computer Science
Subjects
Database Management
Functional Module
Genetic Module
Network Structure
Order Module
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Summary:Biological complexity, and the complexity of a cell in particular, scales only weakly with the number of components. Instead, a cell’s ability to process information, to respond and adapt to an environment in fugue, is directly related to the combinatorially large number of ways genes can be selected and modulated to express its phenotypic repertoire. Viewed in this way it is clear that a cell lacks a fixed network structure, but instead has the potential to form, subject to physical chemical and structurally determined constraints, an extremely large number of environmentally selected networks of genes and proteins with shared components.
ISBN:9783540258667
3540258663
ISSN:0302-9743
1611-3349
DOI:10.1007/11415770_14