Polyurethane Molecular Stamps for the in situ Synthesis of DNA Microarray

O6; Fabrication of polyurethane molecular stamps (PU stamps) based on polypropylene glycol (PPG) and toluene diisocyanate (TDI), using 3, 3(-dichloro-4, 4(-methylenedianiline (MOCA) as the crosslinker, is reported. It was shown from the contact angle measurement that PU stamps surface has good affin...

Full description

Saved in:
Bibliographic Details
Published in中国化学快报(英文版) Vol. 13; no. 9; pp. 883 - 886
Main Authors Nong Yue HE, Chun YANG, Zheng Chun LIU, Zu Hong LU
Format Journal Article
LanguageEnglish
Published Key Lab of New Materials and Technology of China National Packaging Corporation Zhuzhou Engineering College, Zhuzhou 412008%Key Laboratory for Molecular and Bio-molecular Electronics of Ministry of Education, Southeast University, Nanjing 210096 01.09.2002
Key Laboratory for Molecular and Bio-molecular Electronics of Ministry of Education, Southeast University, Nanjing 210096
Subjects
DNA microarray
Molecular stamps
polyurethane
contact angle
soft lithography
Online AccessGet full text

Cover

More Information
Summary:O6; Fabrication of polyurethane molecular stamps (PU stamps) based on polypropylene glycol (PPG) and toluene diisocyanate (TDI), using 3, 3(-dichloro-4, 4(-methylenedianiline (MOCA) as the crosslinker, is reported. It was shown from the contact angle measurement that PU stamps surface has good affinity with acetonitrile, guaranteeing the well distribution of DNA monomers on patterned stamps. Laser confocal fluorescence microscopy images of oligonucleotide arrays after hybridization confirmed polyurethane is an excellent material for molecular stamps when transferring polar chemicals and conducting reactions on interfaces by stamping.
ISSN:1001-8417
1878-5964