Immunoglobulins in Mammary Secretions

Immunoglobulins secreted in colostrum and milk by the lactating mammal are major factors providing immune protection to the newborn. Immunoglobulins in mammary secretions represent the cumulative immune response of the lactating animal to exposure to antigenic stimulation that occurs through interac...

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Bibliographic Details
Published inAdvanced Dairy Chemistry pp. 275 - 294
Main Authors Hurley, W. L., Theil, P. K.
Format Book Chapter
LanguageEnglish
Published Boston, MA Springer US 27.10.2012
Subjects
Bovine Colostrum
Mammary Gland
Passive Immunity
Transepithelial Transport
Ungulate Species
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Summary:Immunoglobulins secreted in colostrum and milk by the lactating mammal are major factors providing immune protection to the newborn. Immunoglobulins in mammary secretions represent the cumulative immune response of the lactating animal to exposure to antigenic stimulation that occurs through interaction with the environment. Extensive species variability exists in how and when maternal immunoglobulins are transferred to the neonate. In addition, there is a range of mechanisms by which the transferred immunoglobulins may play a protective role in the neonate. This chapter reviews the immunoglobulins found in mammary secretions in the context of their diversity of structure, origin, mechanisms of transfer, and function.
ISBN:1461447135
9781461447139
DOI:10.1007/978-1-4614-4714-6_9