Environmentally benign aqueous zinc tetrafluoroborate-catalyzed one-pot Biginelli condensation at room temperature
A trace amount (0.6 mole % with respect to aldehyde or 1,3-dicarbonyl compound) of an aqueous solution of zinc tetrafluoroborate has been used as a mild, efficient and almost neutral catalyst for a one-pot three component condensation of aldehydes, 1,3-dicarbonyl compound and urea or thiourea to aff...
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Published in | Indian journal of chemistry. Sect. B. Organic chemistry, including medicinal chemistry Vol. 48; no. 3; pp. 408 - 412 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
NEW DELHI
Natl Inst Science Communication & Information Resources-Niscair
01.03.2009
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Subjects | |
Online Access | Get full text |
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Summary: | A trace amount (0.6 mole % with respect to aldehyde or 1,3-dicarbonyl compound) of an aqueous solution of zinc tetrafluoroborate has been used as a mild, efficient and almost neutral catalyst for a one-pot three component condensation of aldehydes, 1,3-dicarbonyl compound and urea or thiourea to afford the corresponding 3,4-dihydropyrimidin-2 (1H)-ones (DHPMs) and thiones in high yields at room temperature. |
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ISSN: | 0376-4699 0019-5103 |