A facile route to N-fused pyrrole lactams

N-Fused pyrrole lactams (1a-d) were prepared by substitution and cyclization of methyl 1-(2-bromoethane)pyrrole carboxylate in one-pot. The latter was obtained by treatment of methyl pyrrole-2-carboxylate with excess 1,2-dibromoethane containing NaOH in the presences of PTC.

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Bibliographic Details
Published inJournal of the Indian Chemical Society Vol. 80; no. 8; pp. 790 - 791
Main Authors Zhi, Y, Fu, DC, Shao, RM, Zhang, SF
Format Journal Article
LanguageEnglish
Published CALCUTTA INDIAN CHEMICAL SOC 01.08.2003
Subjects
Chemistry
Chemistry, Multidisciplinary
Physical Sciences
Science & Technology
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Summary:N-Fused pyrrole lactams (1a-d) were prepared by substitution and cyclization of methyl 1-(2-bromoethane)pyrrole carboxylate in one-pot. The latter was obtained by treatment of methyl pyrrole-2-carboxylate with excess 1,2-dibromoethane containing NaOH in the presences of PTC.
ISSN:0019-4522