Biomimetic Mineralization and Degradation of Bioelectret Film in vitro

• Published in: 武汉理工大学学报(材料科学版)英 Vol. 20; no. z1; pp. 83 - 85
• Main Authors: QU Yili, MAN Yi, WANG Peng, CHEN Zhiqing, ZHANG Min, HONG Yujuan, TIAN Kun, YE Yongmei, NIU Ling, ZHU Jianguo, CHEN Qiang, BW Darvell
• Format: Journal Article
• Language: English
• Published: West China College of Stomatology,Sichuang University,Chengdu 610041 ,China%College of Materials Science and Engin-eering,Sichuang University,Chengdu 610000,China%Dental Materials Science,The University of Hong Kong,Hong Kong 01.12.2005
• Subjects: bioelectret; chitosan; degradation; biomimetic mineralization
• ISSN: 1000-2413; 1993-0437

TB3%O484; To explore the behaviour of bioelectret film in mineralization and degradation in vitro, chitosan film was prepared and polarized in an electric field at room temperature. Polarized and unpolarized chitosan films were soaked in 1.5 × SBF (simulated body fluid) solutions for 7, 14 and 28 d at 37 ℃. The negativelycharged surface of the bioelectret film promoted greater mineralization than did unpolarized chitosan. Apatite formation on the surface of the films was identified by X- ray diffraction and scanning electron microscopy. Bioelectret films had a higher rate of degradation than unpolarized material in vitro (pH 7.4, 37 ℃ ) in the presence of 1.5mg/mL lysozyme over 7 d. The electret effect facilitated ths degradation of the film. After 14 d, the degradation rates of the two kinds of film were the same.