Therapeutic blood detoxification via an immunoadsorptive fluidized bed

Agarose-immobilized mouse anti-human B2m monoclonal antibodies (BBM1) incorporated within a vortex flow plasmapheretic reactor (VFPR). Experiments were performed to remove human B2m. The temporal response of the reservoir B2m concentration corresponded to the 10 minute process space-time.

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Bibliographic Details
Published inAnnals of biomedical engineering Vol. 28; no. SUPPL. 1; pp. S - 98
Main Authors Grovender, Eric, Ploegh, Hidde, Cooney, Charlie, Langer, Robert, Rupnik, Maria, Ameer, Guillermo
Format Journal Article
LanguageEnglish
Published 01.01.2000
Subjects
Biological organs
Bioreactors
Blood
Fluidized beds
Immunosensors
Joints (anatomy)
Monoclonal antibodies
Proteins
Tissue
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Summary:Agarose-immobilized mouse anti-human B2m monoclonal antibodies (BBM1) incorporated within a vortex flow plasmapheretic reactor (VFPR). Experiments were performed to remove human B2m. The temporal response of the reservoir B2m concentration corresponded to the 10 minute process space-time.
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ISSN:0090-6964