The long-term clinical efficacy of tumor cytoreduction surgery with hyperthermic intraperitoneal chemotherapy for peritoneal carcinomatosis from colorectal cancer

• Published in: Jie fang jun yi xue za zhi Vol. 45; no. 1; p. 79
• Main Authors: Bo-Yan, LIU, Song-Yan, LI, Hong-Liang, ZHANG, YANG, Yu, TENG, Da, Yi-Chen, LIU, Xiao-Lei, XU, Yu-Xuan, LI, Xiao-Wei, XING, Chang-Zheng, HE, Yu-Feng, WANG, Xiao-Hui, DU
• Format: Journal Article
• Language: Chinese
• Published: Beijing People's Military Medical Press 30.01.2020
• Subjects: Chemotherapy; Colorectal cancer; Ostomy; Surgery
• ISSN: 0577-7402
• DOI: 10.11855/j.issn.0577-7402.2020.01.09

Objective　To study the long-term efficacy of cytoreduction surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) for peritoneal carcinomatosis from colorectal cancer. Methods　The clinical data were collected of 103 patients with peritoneal carcinomatosis (PC) from colorectal cancer undergoing CRS with HIPEC in the Department of General Surgery of the First Medical Center of Chinese PLA General Hospital from January 1, 2012 to May 31, 2013, and divided into colonic group (n=60) and rectal group (n=43) according to the origin position of peritoneal cancer. The surgical status of patients (whether combined with other organ resection, number of stoma, peritoneal carcinomatosis index (PCI), completeness of cytoreduction (CC) score, transfusion, etc.) and the short-term complications and long-term survival after operation in the both groups were compared. Kaplan-meier method was used to draw the survival curve of patients, and log-rank method was employed to compare the survival differences between t