QT Interval Changes in Children With Febrile Convulsion Comparing With Healthy

• Published in: Basic and clinical neuroscience Vol. 14; no. 3
• Main Authors: Teimouri, Alireza, Noor Mohammad Noori, Khajeh, Ali
• Format: Journal Article
• Language: English
• Published: Tehran Negah Scientific Publisher 01.05.2023
• Subjects: Age; Age groups; Children; Pediatrics; Seizures
• ISSN: 2008-126X; 2228-7442
• DOI: 10.32598/bcn.2021.2140.1

Intoduction: A temperature-related seizure is a febrile seizure that affects the QT interval. The purpose of this study was to evaluate the changes in the QT interval caused by febrile convulsion compared with healthy children.Method:This case-control study considered the distribution of 180 children equally shared between patients and controls. The study was conducted at the "Ali Ebne Abi Talib" Hospital in Zahedan, Iran. The disease diagnosed and confirmed based on standard definitions of febrile convulsion. QT interval measured by ECG and interpreted by a pediatric cardiologist and collected data were analyzed with SPSS 19 considering 0.05 as significant error.Results:Among the ECG parameters, HR, R in aVL, S in V3, LVM, QTd, QTc and QTcd were significantly different in children with febrile convulsion compared to the peers. From those who had abnormal QTd, FC children were more frequented but not significant (CHI SQUARE=1.053, p=0.248), when children with FC were more in abnormality regarding QTc (CHI SQUARE=13.032, p<0.001) and QTcd (CHI SQUARE=21.6, P<0.001) significantly. In children with FC, those who were aged less than 12 months, had the highest level of HR but not significant (CHI SQUARE=4.59, p=0.101). Similar trends occurred for R in aVL and S in V3that were higher in the age group >24 months (p>0.05). LVM had the highest value in the age group of >24 months significantly (CHI SQUARE= 52.674, P<0.001) and the other QT parameters were same in Fc children with different age groups (P>0.05).Conclusion:From the study concluded that dispersion corrected QT, corrected QT and dispersion QT changed significantly in children with febrile convulsion in comparing with the healthy children but with constant values in children with FC in different age groups.