Evaluation of Antibacterial Properties of Copper Nanoparticles Surface Coating on Titanium Dental Implant

[...]the use of Ti-6Al-4V alloy has been advocated to improve the mechanical properties (Semiatin et al., 1997). The growing interest in this field is related to the bacterial infection around dental implant which remains as a significant complication (Kalaivani et al., 2014). [...]developing dental...

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Bibliographic Details
Published inJournal of pharmaceutical sciences and research Vol. 10; no. 5; pp. 1157 - 1160
Main Authors Hameed, Hanan Ali, Ariffin, Azirrawani, Luddin, Norhayati, Husein, Adam
Format Journal Article
LanguageEnglish
Published Cuddalore Journal of Pharmaceutical Sciences and Research 01.05.2018
Subjects
Antibiotics
Antimicrobial agents
Bacteria
Dental implants
Hydroxyapatite
Infections
Kinases
Mechanical properties
Microorganisms
Nanoparticles
Physical properties
Studies
Titanium alloys
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Summary:[...]the use of Ti-6Al-4V alloy has been advocated to improve the mechanical properties (Semiatin et al., 1997). The growing interest in this field is related to the bacterial infection around dental implant which remains as a significant complication (Kalaivani et al., 2014). [...]developing dental material with high antibacterial property helps to decrease or limit the growth of any bacteria, even after treatment in infected defects. The antibacterial property improves greatly when using Cu2+ particles in nanosize as demonstrated by (Medina et al., 2007; Grass et al., 2011) Likewise, in the present study, the Cu2+ and HA particles were synthesized in nanoparticles to improve their bactericidal effect by increasing the contact surface area against P. gingivalis. [...]the exact mechanism of bacterial cell death by Cu nanoparticles is not entirely understood. According to this study, copper ion doped hydroxyapatite (Cu/HA) in nanoparticles is considered highly effective as an antibacterial agent and Titanium surface modification with this material can be recommended as an attractive coating for local control of infection around dental implant.
ISSN:0975-1459