Evaluation of the Combined Effect Onethanolic Extracts of Pisoniagrandis and Cardiospermumhalicacabum Inanti-Arthritic, Anti-Inflammatory and Analgesic Activities

The non-steroidal drugs used for the treatment of pain and inflammation may causes some disorders like ulceration, hemorrhage, kidney and liver dysfunction. [...]plant-based medicines with analgesic and anti-inflammatory properties have been used for a long time with no negative side effects when co...

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Published inAnnals of the Romanian society for cell biology Vol. 25; no. 3; pp. 8034 - 8049
Main Authors Chokkalinagam, Priya, Sekar, Karthikeyan, Masilamani, Sri Devi, Deepalakshmi, P S, Kumar, G Mohan, Hari, Rajeswary
Format Journal Article
LanguageEnglish
Published Arad "Vasile Goldis" Western University Arad, Romania 01.01.2021
Subjects
Albinism
Analgesics
Animals
Anti-inflammatory agents
Arthritis
Cellular biology
Disease
Edema
Flowers & plants
Hemorrhage
Herbal medicine
Immunology
Inflammation
Liver diseases
Medicinal plants
Mortality
Pain
Rheumatism
India
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Summary:The non-steroidal drugs used for the treatment of pain and inflammation may causes some disorders like ulceration, hemorrhage, kidney and liver dysfunction. [...]plant-based medicines with analgesic and anti-inflammatory properties have been used for a long time with no negative side effects when comparing to synthetic drugs with same properties7,8. [...]a comprehensive pharmacological assessment and documentation of plants which are used in the herbal medicine is required8. Rheumatism, nervous disorders, limb weakness, and snakebite are among the conditions for which Cardiospermumhalicacabum is recommended. [...]successful formulations must be created using indigenous medicinal plants in conjunction with appropriate pharmacological studies and clinical trials10, 11. Since Pisoniagrandis and Cardiospermumhalicacabum have a long history of use in the treatment of arthritis and have been clinically tested for their potency individually, the current research aims to determine their synergistic invivoanti-arthritic, antiinflammatory and analgesic activity of the Bi-herbal ethanolic extract (BHE) which contain equal amount of leaves of Pisoniagrandisand Cardiospermumhalicacabum with ethanolic extract extracts of Pisoniagrandis(EPG) and Cardiospermumhalicacabum (ECH).
ISSN:2067-3019
2067-8282