Antioxidative and cytotoxic activities of crude and isolated compounds of P. Lateriflora (bl.) King

According to the phytochemical survey of 'Malaysian Herbarium on Flora of Malaysia' this plant is dominant locally at the area of Hutan Simpan Bukit Kinta, Chemor, Perak. Several species of the genus Polyalthia have been reported to have various medicinal properties, including antioxidant...

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Published inJournal of pharmaceutical sciences and research Vol. 10; no. 11; pp. 2718 - 2721
Main Authors Obaid, Ahmed Kareem, Azziz, Saripah Salbiah Syed Abdul, Bakri, Yuhanis Mhd, Nafiah, Mohd Azlan, Awang, Khalijah, Aowda, Saadon Abdulla, Hassan, Norazian Mohd, Hashim, Yumi Zuhanis Has-Yun, Abdullah, Fauziah
Format Journal Article
LanguageEnglish
Published Cuddalore Journal of Pharmaceutical Sciences and Research 01.11.2018
Subjects
Antioxidants
Breast cancer
Chemistry
Chromatography
Cytotoxicity
DNA damage
Phytochemicals
Silica
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Summary:According to the phytochemical survey of 'Malaysian Herbarium on Flora of Malaysia' this plant is dominant locally at the area of Hutan Simpan Bukit Kinta, Chemor, Perak. Several species of the genus Polyalthia have been reported to have various medicinal properties, including antioxidant [4], anticancer [5,6,7], antibacterial [8,9], antifungal [10], antiulcer [11], lipid lowering agent [12], protective effect against oxidative DNA damage [13] and antiplasmodial [14]. Aluminum supported silica gel 60 F254 plates were used for thin-layer chromatography (TLC), visualized under ultraviolet light (254 and 365 nm), and sprayed using Dragendorff's reagent for alkaloid test and p-anisaldehyde reagent for steroid test. "In vitro cytotoxic potential of Polyalthia longifolia on human cancer cell lines and induction of apoptosis through mitochondrial dependent pathway in HL-60 cells", Chem.
ISSN:0975-1459