Evaluation of microRNAs expression (miR-16 and miR-199a) in serum of endometriotic patients

[...]this study demonstrated that the levels of circulating miRNAs (miR-199a and miR-16) could serve as noninvasive tools for diagnosis of endometriosis. [...]a serum miRNA-based test is low cost and sample management is easy, including sample collection and processing [7]. [...]these miRNAs may be...

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Bibliographic Details
Published inJournal of pharmaceutical sciences and research Vol. 10; no. 5; pp. 1128 - 1132
Main Authors Shamkhi, Jinan Abdul-abbas, Abbas, Ahmed Abdul-hassan, Al-Deen, Thuraya Hussam
Format Journal Article
LanguageEnglish
Published Cuddalore Journal of Pharmaceutical Sciences and Research 01.05.2018
Subjects
Angiogenesis
Biomarkers
Disease
Endometriosis
Gene expression
Gynecology
Inflammatory diseases
Kinases
Menstruation
MicroRNAs
Obstetrics
Pediatrics
Software
Statistical analysis
Teaching hospitals
Womens health
United States > US
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Summary:[...]this study demonstrated that the levels of circulating miRNAs (miR-199a and miR-16) could serve as noninvasive tools for diagnosis of endometriosis. [...]a serum miRNA-based test is low cost and sample management is easy, including sample collection and processing [7]. [...]these miRNAs may be useful for diagnosing disease severity, although this will require validation in a large cohort of samples. [...]the present study highlighted the possibility of using combined serum miRNA for management of endometriosis [7]. [...]studies on the expression, regulation and function of miRNAs in patients with endometriosis will provide the unique insights for the development of specific miRNAs as diagnostic markers and therapeutic targets for endometriosis in the future [24].
ISSN:0975-1459