An ultrastructural comparison of human endometrial adenocarcinoma with normal postmenopausal endometrium

Although electron microscopy has been of limited value in detecting malignant neoplasms, some neoplasms do exhibit characteristic ultrastructural features. Intensive study of these features may offer insight into the etiology and activity of such tumors. In an attempt to characterize the ultrastruct...

Full description

Saved in:
Bibliographic Details
Published inObstetrics and gynecology (New York. 1953) Vol. 53; no. 5; p. 565
Main Authors Aycock, N R, Jollie, W P, Dunn, L J
Format Journal Article
LanguageEnglish
Published United States 01.05.1979
Subjects
Adenocarcinoma - ultrastructure
Endometrium - ultrastructure
Endoplasmic Reticulum - ultrastructure
Female
Humans
Menopause
Microscopy, Electron
Mitochondria - ultrastructure
Uterine Neoplasms - ultrastructure
Online AccessGet more information

Cover

More Information
Summary:Although electron microscopy has been of limited value in detecting malignant neoplasms, some neoplasms do exhibit characteristic ultrastructural features. Intensive study of these features may offer insight into the etiology and activity of such tumors. In an attempt to characterize the ultrastructure of endometrial adenocarcinoma, tissue was examined with the electron microscope and compared with normal postmenopausal endometrium. Endometria from biopsy, hysterectomy, or curettage were processed routinely for light and electron microscopy. Several ultrastructural features of the adenocarcinoma were common both to previous descriptions of endometrium of the postovulatory phase and to the normal postmenopausal endometrium, described here, viz, atypical mitochondrial forms and cell surface modifications. Ribosomes were abundant in adenocarcinoma of the endometrium, normal postmenopausal endometrium, and normal cyclic endometrium in the preovulatory phase.
ISSN:0029-7844
1873-233X