Chondroblastoma

Chondroblastom, benign cartilage tissue neoplasm, accounts for 1% of all bone tumors. It is encountered in any skeletal bones mainly in persons aged 10 and 25 years. Morphologically, it is represented as large homogenous cells--well-defined oval polygonal chondroblasts with a fine eosinophilic cytop...

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Bibliographic Details
Published inArkhiv patologii Vol. 69; no. 3; p. 53
Main Authors Bulycheva, I V, Semenov, L A, Makhson, A N, Zhukov, A G
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.05.2007
Subjects
Adult
Bone Neoplasms - diagnostic imaging
Bone Neoplasms - genetics
Bone Neoplasms - therapy
Child
Chondroblastoma - diagnostic imaging
Chondroblastoma - genetics
Chondroblastoma - therapy
Humans
Prognosis
Radiography
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Summary:Chondroblastom, benign cartilage tissue neoplasm, accounts for 1% of all bone tumors. It is encountered in any skeletal bones mainly in persons aged 10 and 25 years. Morphologically, it is represented as large homogenous cells--well-defined oval polygonal chondroblasts with a fine eosinophilic cytoplasm, and a round-to-oval nucleus. Cartilaginous portions of chondroblastoma form lobular structures. The tumor always comprises single-to-multiple multinucleate giant cells. The pathognomonic sign of chondroblastoma is intercellular reticular basophilically stained calcifications as a mesh. Mitotic cells, rather than abnormal ones, are present. There are cases of primary malignant chondroblastomas.
ISSN:0004-1955