Analysis of clinical feature and treatment outcome in 42 patients with lymphoblastic lymphoma
To investigate the clinical features and treatment outcomes of different regimens in Chinese patients with lymphoblastic lymphoma (LBL). Forty-three patients with LBL were retrospectively analysed, of which 30 were T-LBL, and 13 B-LBL. (1) Most patients were young men with a median age of 21, and 63...
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Published in | Zhōnghuá xuèyèxué zázhì Vol. 30; no. 7; p. 446 |
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Main Authors | , , , , , , |
Format | Journal Article |
Language | Chinese |
Published |
China
01.07.2009
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Abstract | To investigate the clinical features and treatment outcomes of different regimens in Chinese patients with lymphoblastic lymphoma (LBL).
Forty-three patients with LBL were retrospectively analysed, of which 30 were T-LBL, and 13 B-LBL.
(1) Most patients were young men with a median age of 21, and 63.0% of the T-LBL patients had mediastinal masses. (2) Treatment outcome could be assessed in 37 cases, of which the response rate (RR) was 81.1% and complete remission (CR) rate was 67.6%. The RR and CR rates in patients treated with regimens for ALL (ALL-like group) and those treated with regimens for NHL (NHL-like group) were 94.4%, 68.4% and 83.3%, 52.6%, respectively. (3) The estimated median overall survival (OS) and progression free survival (PFS) of hematopoietic stem cell transplantation (HSCT) group were significant longer than those of ALL-like group (P=0.018, P=0.025) and NHL-like group (P=0.016, P=0.011). The OS at 5 years in NHL-like group, ALL-like group and HSCT group were (14.4+/-9.4)%, (20.2+/-12.7 |
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AbstractList | To investigate the clinical features and treatment outcomes of different regimens in Chinese patients with lymphoblastic lymphoma (LBL).
Forty-three patients with LBL were retrospectively analysed, of which 30 were T-LBL, and 13 B-LBL.
(1) Most patients were young men with a median age of 21, and 63.0% of the T-LBL patients had mediastinal masses. (2) Treatment outcome could be assessed in 37 cases, of which the response rate (RR) was 81.1% and complete remission (CR) rate was 67.6%. The RR and CR rates in patients treated with regimens for ALL (ALL-like group) and those treated with regimens for NHL (NHL-like group) were 94.4%, 68.4% and 83.3%, 52.6%, respectively. (3) The estimated median overall survival (OS) and progression free survival (PFS) of hematopoietic stem cell transplantation (HSCT) group were significant longer than those of ALL-like group (P=0.018, P=0.025) and NHL-like group (P=0.016, P=0.011). The OS at 5 years in NHL-like group, ALL-like group and HSCT group were (14.4+/-9.4)%, (20.2+/-12.7 |
Author | Li, Qian Qui, Lu-Gui Zhao, Yao-Zhong Xu, Yan Lu, Bin Qi, Jun-Yuan Zou, De-Hui |
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BackLink | https://www.ncbi.nlm.nih.gov/pubmed/21678570$$D View this record in MEDLINE/PubMed |
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Snippet | To investigate the clinical features and treatment outcomes of different regimens in Chinese patients with lymphoblastic lymphoma (LBL).
Forty-three patients... |
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Title | Analysis of clinical feature and treatment outcome in 42 patients with lymphoblastic lymphoma |
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