A Case of Neonatal Myeloid Sarcoma

Here we describe a cutaneous neonatal myeloid sarcoma (MS) case with a subsequent diagnosis of acute myeloid leukemia (AML) seven days later. Cytogenetic studies were unusual demonstrating a triple copy of KAT6A abnormality and complex 8;14;22 translocation involving the 8p11.2 region. MS may be the...

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Bibliographic Details
Published inSouth Dakota medicine Vol. 75; no. 9; p. 390
Main Authors Burdick, Halie, Bormann, Jordan, Wagner, KayeLyn, Kerkvliet, Amy
Format Journal Article
LanguageEnglish
Published United States 01.09.2022
Subjects
Histone Acetyltransferases
Humans
Infant, Newborn
Sarcoma, Myeloid - diagnosis
Skin Neoplasms - diagnosis
Skin Neoplasms - genetics
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Summary:Here we describe a cutaneous neonatal myeloid sarcoma (MS) case with a subsequent diagnosis of acute myeloid leukemia (AML) seven days later. Cytogenetic studies were unusual demonstrating a triple copy of KAT6A abnormality and complex 8;14;22 translocation involving the 8p11.2 region. MS may be the initial finding suggesting associated AML; therefore, the diagnosis of cutaneous MS may allow for expeditious evaluation/treatment of such leukemic disorders.
ISSN:0038-3317