Clinical and therapeutic considerations in pseudomyxoma peritonei

• Published in: Chirurgia (Bucharest, Romania : 1990) Vol. 93; no. 1; p. 27
• Main Authors: Constantinoiu, S, Chiru, F, Mateş, I N, Pop, D, Cochior, D, Bârlă, R, Dinu, D, Predescu, D, Predescu, V
• Format: Journal Article
• Language: English; Romanian
• Published: Romania 01.01.1998
• Subjects: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols - therapeutic use; Chemotherapy, Adjuvant; Female; Humans; Intraoperative Care; Middle Aged; Ovarian Neoplasms - diagnosis; Ovarian Neoplasms - drug therapy; Ovarian Neoplasms - pathology; Ovarian Neoplasms - surgery; Peritoneal Neoplasms - diagnosis; Peritoneal Neoplasms - drug therapy; Peritoneal Neoplasms - pathology; Peritoneal Neoplasms - surgery; Pseudomyxoma Peritonei - diagnosis; Pseudomyxoma Peritonei - drug therapy; Pseudomyxoma Peritonei - pathology; Pseudomyxoma Peritonei - surgery; Retrospective Studies
• ISSN: 1221-9118

Pseudomyxoma peritonei (PMP) is an uncommon clinical entity, lacking a precisely defined etiopathogenesis. Its clinical features are not specific and diagnosis is difficult. We analysed 10 patients, all of them women, whom we had treated surgically in combination with intraperitoneal chemotherapy. Postoperative complications had been minimal and no death had occurred. 5 patients were followed up in time, 4 of them presenting a favourable evolution (2 required reintervention), and 1 patient decreased. We analysed up-to-date therapeutic approaches and the benefit of their combinations in order to identify the optimal therapeutic strategy. We consider that the combinations surgery + intraperitoneal chemotherapy or surgery + intracavitary radiotherapy are the most effective up to date.