Severe liver degeneration in mice lacking the (I kappa B) kinase 2 gene

Phosphorylation of inhibitor kappa B (IkappaB) proteins is an important step in the activation of the transcription nuclear factor kappa B (NF-kappaB) and requires two IkappaB kinases, IKK1 (IKKalpha) and IKK2 (IKKBeta).

Saved in:
Bibliographic Details
Published inScience (American Association for the Advancement of Science) Vol. 284; no. 5412; pp. 321 - 325
Main Authors Li, Qiutang, Van Antwerp, Daniel, Mercurio, Frank, Lee, Kuo-Fen, Verma, Inder M
Format Journal Article
LanguageEnglish
Published Washington The American Association for the Advancement of Science 09.04.1999
Subjects
Birth defects
Genes
Genetics
Individualized Instruction
Laboratory animals
Liver
Pregnancy
Rodents
Online AccessGet full text

Cover

More Information
Summary:Phosphorylation of inhibitor kappa B (IkappaB) proteins is an important step in the activation of the transcription nuclear factor kappa B (NF-kappaB) and requires two IkappaB kinases, IKK1 (IKKalpha) and IKK2 (IKKBeta).
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ObjectType-Article-2
ObjectType-Feature-1
ISSN:0036-8075
1095-9203